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Electrophoresis-based Chemical Separation and Purification Service

Electrophoresis is an advanced technology that utilizes the difference in migration rates of charged particles under the action of an electric field to achieve efficient separation and purification of chemical substances. Based on the deep accumulation in the field of green chemistry, CD BioSciences-GreenChemistry provides custom electrophoretic separation and purification services in various fields, such as pharmaceuticals, new materials, environmental protection, and food science, to clients.

What Is Electrophoresis?

Electrophoresis is a technique for the separation and purification of chemical substances under the action of an electric field, using the difference in migration rates of charged particles in the electric field. The method is easy to operate, has high separation efficiency, and is environmentally friendly. It can effectively separate different components of a complex chemical system in a short period, and the separation process does not require the use of large amounts of organic solvents, which greatly reduces the pollution of the environment.

Fig.1 The many types of electrophoresis methods.Fig.1 Multiple types of electrophoresis methods based on different classification criteria. (CD BioSciences-GreenChemistry)

Our Professional Services

As a green chemistry company, CD BioSciences-GreenChemistry provides professional chemical separation and purification services by electrophoresis. Our services cover the whole process from sample preparation, and electrophoresis operation to result analysis, ensuring that clients can obtain high quality and purity target compounds.

Steps in the separation and purification of chemicals by electrophoresis.Fig.1 Multiple types of electrophoresis methods based on different classification criteria. (CD BioSciences-GreenChemistry)

  • Sample Preparation

Depending on the nature of the chemicals, we select the appropriate solvent and method for extraction. Then the extracted samples are subjected to necessary pre-treatment, such as removing impurities, adjusting pH, adding buffer, etc., to optimize the electrophoretic effect.

For chemicals that require special identification, we perform labeling processes, such as fluorescent labeling, isotope labeling, etc., to facilitate subsequent detection and analysis.

  • Electrophoretic Separation

We provide suitable electrophoresis systems to meet different separation and purification requirements, including but not limited to sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), capillary electrophoresis (CE), isoelectrofocusing electrophoresis (IEF), and so on.

At the same time, we also carefully set the appropriate electrophoresis conditions, such as voltage, current, electrophoresis time, etc., according to the nature of the chemicals, the characteristics of the electrophoresis system, and the target separation effect. After everything is ready, we start the electrophoresis system and carry out the electrophoresis operation strictly according to the set conditions until the expected separation effect is achieved.

  • Result Analysis

After the chemicals have been separated, we record the electrophoretic profiles using appropriate assays (e.g., fluorescence detection, isotope detection, etc.) to ensure that the profiles are clear and accurate. We also analyze the electrophoretic profiles to identify and determine the molecular weight and purity of the target compounds.

Applications

  • Materials Science: Our services are used in the development of anticorrosive, decorative, and protective coatings for metal surfaces.
  • Environmental Science: Our services can be used to efficiently separate and purify pollutants in the environment, providing strong support for environmental pollution control.
  • Food Safety: Our services can be used for the separation and detection of nutrients, additives, and contaminants in food.

Advantages

  • Advanced Electrophoresis Technologies: We have mastered and continuously optimized various electrophoresis technologies to meet the needs of different chemical separation and purification.
  • Customized Electrophoresis Solutions: According to the specific needs of clients and the nature of chemical substances, we provide custom electrophoresis solutions to ensure the best separation results.
  • Professional R&D Team: We have an R&D team consisting of experts in the fields of electrochemistry and analysis chemistry, which is capable of responding quickly to clients' needs and providing high-quality technical support.

As a pioneer in the field of green chemistry, CD BioSciences-GreenChemistry provides efficient and environmentally friendly chemical separation and purification services based on advanced electrophoresis technology, aiming to accurately capture every molecular mystery for clients. No matter what your needs or questions are, please feel free to contact us, and let's start a new chapter of green chemistry together!

Reference

  1. Skotnicki W, Jędrzejczyk D. The comparative analysis of the coatings deposited on the automotive parts by the cataphoresis method[J]. Materials. 2021, 14(20): 6155.

Our products and services are for research use only and cannot be used for any clinical purposes.