logo

Green Aspiration Level Assessment Service

Green aspiration level (GAL) is an effective tool to measure the degree of process greening. CD BioSciences-GreenChemistry provides a GAL assessment service to comprehensively evaluate the degree of greenness of production processes in the chemical and pharmaceutical industries by integrating key metrics such as well-defined synthetic starting points, environmental factors in the complete process, and the complexity of the process for ideal synthesis of the drug.

Overview of Green Aspiration Level

Fig.1 Impacts on the environment from the life cycle of plastics (PFAS are perfluorinated and polyfluoroalkyl compounds).

Green aspiration level (GAL) is a quantitative tool designed to measure the degree of greening of chemical substance production processes. The GAL primarily measures the environmental impacts of chemical substance production processes throughout the life cycle, especially the reduction of waste emissions. It aims to guide the optimization of production processes to reduce the environmental burden and achieve sustainable development.

As an innovative measurement tool, GAL can be used not only to assess the degree of greening of existing processes but also to guide the development and optimization of new processes. Overall, GAL provides clear greening goals and improvement strategies for companies and organizations in drug discovery as well as chemical manufacturing and is an important tool for promoting green and sustainable development in the industry.

Our Professional Services

CD BioSciences-GreenChemistry's GAL assessment service for clients is a systematic and refined assessment process designed to deeply analyze and quantify the degree of greenness of production processes.

Workflow of GAL Assessment Service

Fig.1 Impacts on the environment from the life cycle of plastics (PFAS are perfluorinated and polyfluoroalkyl compounds).

Analyzing Synthesis Starting Points

We clearly define the starting feedstock for the synthesis reaction based on industry standards and process information provided by the client. This includes confirming that the feedstock price meets a preset threshold and that the feedstock is included in a common feedstock catalog.

Complete Process Environmental Factor (EF) Calculation

We use the Process Mass Intensity assessment model, combined with detailed process parameters and raw material consumption data, to calculate the EF of the complete process. This step involves a comprehensive consideration of all material and energy flows in the process to fully reflect the environmental impact of the process.

Synthetic Process Complexity Assessment

We analyze in depth the complexity of the synthetic route, including the key reaction steps that form C-C and C-H bonds, as well as strategic redox processes. The number and type of these steps together determine the complexity of the synthesis process.

GAL Calculation

Based on the historical average value of waste generated from the production of the chemical substance in question as a benchmark, we compare the EF value of the target process and combine it with the results of the complexity assessment to calculate the GAL.

Applications


  • Pharmaceutical Process Optimization: Accurately quantify the environmental impact of drug production and guide process greening improvements.
  • Fine Chemicals Synthesis: Evaluate the greenness of synthesis routes and promote environmentally friendly product development.
  • Agricultural Chemicals Assessment: Improve the green safety of agricultural inputs such as pesticides and fertilizers to protect the ecological environment.
  • Material Innovation: Help green design in the R&D process of new materials and reduce environmental pollution.

Advantages

  • Advanced Technology: We use cutting-edge green chemistry assessment technology to ensure the accuracy of assessment results.
  • Professional Team: We have a team of senior chemists and environmental engineers with in-depth industry knowledge.
  • Comprehensive Services: We provide one-stop assessment and optimization services from starting material analysis to process complexity assessment.

With advanced technology, a professional team, authoritative experts, and rich experience, CD BioSciences-GreenChemistry provides comprehensive g GAL assessment services. Our services accurately quantify the degree of greening of processes and help clients realize environmentally friendly production. Please feel free to contact us if you need to green your production.

Reference

  1. Zimmerman J B, Anastas P T, et al. Designing for a green chemistry future[J]. Science. 2020, 367: 397-400.

Our products and services are for research use only and cannot be used for any clinical purposes.