Green Chemistry Technology Platform

CD BioSciences-GreenChemistry's green chemistry technology platform, led by senior research experts, integrates cutting-edge green technologies such as electrochemistry, photochemistry, enzyme catalysis continuous production, etc. into the chemical synthesis routes of various chemical molecules to achieve environmentally optimized and sustainable synthetic reactions.

Overview of Green Chemistry Technology

Diagram of the application of green chemistry. (CD BioSciences-GreenChemistry)

Green chemistry, also known as environmentally sound chemistry, is the science of stopping environmental pollution at its source. Technologies innovated on its basis are called green chemistry technologies, environmentally friendly technologies, or clean technologies. The most ideal green chemistry technology is the adoption of the “atom economy” reaction, which realizes the greening of the reaction, that is, every atom in the raw material molecule is transformed into a product without producing any waste and by-products, thus realizing “zero emission” of waste.

Applications of Green Chemistry Technology

Green chemistry technology aims to minimize the effects of chemical processes on the environment and facilitates maximum utilization of resources through creative methods while also guaranteeing that the products are sustainable and safe. This sort of technology, at this point, has been quite customary for some time now:

Diagram of the application of green chemistry. (CD BioSciences-GreenChemistry)

Our Green Chemistry Technology Platform

CD BioSciences-GreenChemistry has constructed a green chemistry technology platform based on the strengths of professional team and project experience and has comprehensively utilized advanced technologies such as enzyme catalysis, serialization, photochemistry and electrochemistry, etc. to develop highly efficient and green chemicals and related synthetic processes to create value for customers in a sustained manner.

Chemical Production Technology Platform

Our R&D team has extensive project experience in the extraction and production of various chemical substances using a variety of green chemistry technologies.

Solvent-free or Solvent-minimized Extraction Technology

Through in-depth scientific research and experiments, we determine the optimal extraction conditions to improve efficiency and yield. We utilize advanced equipment for physical methods of treatment, such as heat, high pressure, and ultrasound, to effectively release target compounds.

Biocatalytic Production Technology

We select suitable biocatalysts to reduce the by-products and energy consumption that may be generated in conventional chemical reactions. We optimize enzyme classes and reaction conditions (temperature, pH) through in-depth experiments to ensure that the solutions we provide are efficient and environmentally friendly.

Solid Phase Catalytic Production Technology

We use solid catalysts instead of liquid-phase catalysts to facilitate catalyst recovery and reuse. In the process, we adjust the conditions of reaction temperature, pressure, and time to maximize the efficiency of the reaction, and lowering the carbon footprint of the production process.

Photochemical Production Technology

We fully utilize light energy as the primary source of reaction drive to produce chemicals that meet our client's needs. We maximize the utilization of light energy by precisely regulating light reaction conditions, such as light intensity and wavelength, to ensure efficient chemical reactions and increased yields.

Electrochemical Production Technology

Based on the characteristics of our client's projects, we design electrochemical reaction pathways to maximize reaction efficiency while reducing energy consumption. We use renewable energy to power the electrochemical production process, emphasizing the use of clean energy to further reduce carbon footprint.

Enzyme-catalyzed Reaction Technology Platform

We have established an enzyme-catalyzed process platform through a competent biotechnology R&D team, with great success. The enzyme-catalyzed platform construct integrates enzyme constructing, enzyme fermenting, enzyme screening, micro-volume ratio, catalytic process optimization, and scaling up production, giving clients access to high throughput small molecule synthesis using enzyme catalysts and other services.

Process flow of an enzyme-catalyzed technology platform.Fig.1 Flow chart of our enzyme-catalyzed process. (CD BioSciences-GreenChemistry)

Photochemical Catalyzed Reaction Technology Platform

Using photo-activated reactions as a tool, we are developing and expanding the reach of photo-reactions by improving the efficiency of the process and meeting the required extent. Achieving a range of chemical reactions, cis-trans isomerization of olefins, addition, halogenation, elimination, and ring opening of rings.

Capacity in Photochemical Reaction Engineering

  • Reactors: We have small photoreactors for small-scale laboratory reactions, as well as large factory-based photoreactors with capacities of more than 10 kg per day.
  • Temperature Control Range: -30 to 180°C
  • Light Source: Mercury or Xenon
  • Light Power: 100 to 1000W
  • Photocatalysts: A collection of common metal and organic catalysts, continually expanded based on the literature.

Electrochemical Catalyzed Reaction Technology Platform

We have electrochemical methods with outstanding advantages such as easy miniaturization, high sensitivity, suitability for non-transparent samples, and low power requirements for power supplies, which are suitable for the construction of miniaturized analytical devices. Based on electrochemical technology, we also provide our clients with the ability to construct a variety of chemical reactions used in the production of chemical substances:

  • Ni-Catalyzed C-N Coupling
  • Ni-Catalyzed Sp2-Sp3 Coupling
  • C-H Oxidations
  • Reduction of Amide
  • Heterocycles Formation

Catalyst Screening Technology Platform

Catalysts are widely used in coupling reactions and asymmetric synthesis. To improve the efficiency of route exploration and condition optimization, we construct a catalyst screening technology platform to provide clients with chemical small molecule production and screening services. Through reliable catalyst parallel screening, we obtain reaction results with different catalysts, ligands, bases, solvents, and temperatures in a short time with tens of milligrams or even smaller amounts of intermediates.

Green Analysis Technology Platform

Our analysis technology platform uses green techniques for the comprehensive analysis of a wide range of chemical substances. Our green analysis services cover the full range of stages from sample preparation, chemical separation and purification, to performance analysis. Details can be found in the table below:

Specific Operations Green Analysis Technologies
Sample Preparation Stage Microwave Digestion Technology
Microwave Extraction Technology
Supercritical Fluid Extraction Technology
Compound Separation and Enrichment Stage Solid Phase Extraction Technology
Solid Phase Microextraction Technology
Liquid Membrane Extraction Technology
Membrane Extraction Technology with Adsorption Interfaces
Purge & Trap (P&T) Technology
Compound Analysis Stage Near Infrared (NIR) Technology
Neutron Activation Technology
Capillary Electrophoresis Technology
Chromatography Technology

Microchannel Continuous Reaction Technology Platform

Our microchannel continuous reaction technology platform has a wide range of modular equipment that can be flexibly assembled according to our client's process needs for environmentally friendly and continuous process development and production. Our platform provides clients with continuous chemical reaction processes such as organolithiation, oxidation, diazotization, azide, nitrification, continuous hydrogenation, etc., to ensure that our client's project requirements are met.

Our Advantages

  • Our green chemistry platform significantly reduces waste generation and enables efficient use of resources.
  • Through the use of advanced catalytic technologies, our chemical reactions use less energy and significantly reduce our carbon footprint.
  • Our platform supports the use of renewable feedstocks and promotes sustainable green chemistry practices.
  • Our technology platform is flexible and adaptable, allowing us to customize solutions to meet diverse production needs.

CD BioSciences-GreenChemistry's green chemistry platform integrates a variety of advanced technologies to ensure efficient and sustainable chemical reactions. Meanwhile, our platform supports customized services and provides a full range of technical support and solutions to our clients. Welcome clients to contact us at any time to explore collaboration opportunities and jointly promote the application of green technologies.

Reference

  1. Donato L, Nasser II, Majdoub M, et al. Green chemistry and molecularly imprinted membranes[J]. Membranes. 2022, 12(5): 472.

Our products and services are for research use only and cannot be used for any clinical purposes.