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Precipitation-based Chemical Separation and Purification Service

Precipitation is a widely used approach to separate and purify chemical substances. Because of its ease and reliability, precipitation is employed in mineralogy, materials engineering, and chemical preparation procedures. The CD BioSciences-GreenChemistry specialists apply their extensive experience in solving chemistry problems through precipitation, turning it into a tool for a wide variety of chemical separations and purifications.

What Is the Precipitation Method?

Schematic diagram of the chemical precipitation method.

The method of precipitation relies on precipitation reactions. In this case, the method of precipitation involves adding a chemical reagent to a separated solution to cause some of its substances to precipitate. Specifically, this method consists of combining a chemical reagent to achieve a chemical reaction that yields an insoluble compound, wherein both a precipitate and an insoluble compound are produced from the solution. Filtration or centrifugation may be used to remove this precipitate, and further purification may involve washing and drying.

Application of Precipitation Methods

  • Heavy Metal Removal: Precipitation can be used to remove heavy metal ions from solvents, i.e. separation of impurities and products is achieved through the formation of insoluble compounds.
  • Solvent Recovery: In chemical production, precipitation can be used to recover and reuse organic solvents to improve resource utilization.
  • Pharmaceutical Industry: In the pharmaceutical industry, precipitation can be used to purify active ingredients from mixtures to ensure the quality of pharmaceuticals.
  • Food Processing: Precipitation technology can be used to remove unnecessary ingredients from food products to improve purity and safety.

Our Professional Services

CD BioSciences-GreenChemistry offers environmentally friendly separation and purification services based on precipitation methods with a dedicated team of professionals committed to green chemistry services. We offer precipitation methods that efficiently separate target compounds while minimizing chemical reagent use and waste generation.

  • Precipitation Purification of Inorganic Compounds

Schematic diagram of inorganic compounds.

We purify inorganic compounds by dissolving them in an appropriate amount of solvent and adding a suitable precipitant to them to cause them to form a precipitate. We select a suitable precipitant according to the chemical properties of the inorganic compound and accelerate the precipitation process by heating or adjusting the pH. For example, in a solution containing Fe3+, NaOH is added to produce Fe(OH)3 precipitate, which in turn purifies iron from the aqueous solution.

  • Precipitation and Purification of Small Organic Molecules

We separate and purify organic molecules by changing the solvent conditions, and temperature or adding precipitants to produce precipitation. For example, the crude raw material of pharmaceutical small molecule aspirin can be dissolved in green solvents such as alcohols, and changing its temperature and adding water to cool it can cause the target compound to undergo precipitation. After filtration and drying, high-purity aspirin can be obtained.

Schematic diagram of the structure of an organic molecule.

  • Precipitation Purification of Macromolecular Compounds

Schematic diagram of the structure of macromolecular compounds.

Depending on the nature of the macromolecular compounds, we use suitable precipitants such as ethanol, acetone, or polyethylene glycol. Under constant stirring, we slowly add the precipitating agent to the compound solution and make it fully form a precipitate by adjusting the temperature and pH. The precipitation method we offer can be used to isolate and purify macromolecular compounds such as proteins, nucleic acids, and polysaccharides.

Advantages of Services We Offer

  • Use of Green Reagents: We use environmentally friendly reagents as precipitants, avoiding the use of toxic and hazardous chemicals.
  • High Selectivity: We offer precipitation methods with high selectivity and good purification efficiency, reducing waste generation.
  • Simple to Implement: Our process for purifying chemicals by precipitation is simple and easy to implement in different sizes of laboratories or industrial environments.

CD BioSciences-GreenChemistry works tirelessly to meet the ever-increasing demand for chemical purification technologies while remaining economically viable and environmentally friendly. Our processes and technology are sophisticated and novel, but more importantly, they are clean and ecologically responsible. We welcome you to contact us at any time to create a better tomorrow!

Reference

  1. Li J, Wang Y, et al. Selective Complex precipitation for ferro-chrome separation from electroplating sludge leaching solution[J]. Frontiers in Chemistry. 2021, 9: 592407.

Our products and services are for research use only and cannot be used for any clinical purposes.