Photochemical Reaction Technology Platform

Photochemical reaction technology is a process technology that relies on the absorption of light energy by a reactive system for chemical synthesis reactions. CD BioSciences-GreenChemistry's cutting-edge photochemical reaction technology platform uses light as a pen to draw a blueprint for green chemistry, leading clients into a new era of innovative synthesis. We help our clients achieve excellence in synthesizing complex molecules, efficient catalysis, and environmentally friendly processes, making every ray of light a driving force for sustainable development.

What Is a Photochemical Reaction?

Photochemical reaction refers to a chemical reaction triggered by the absorption of photon energy by the reactants under visible or ultraviolet light and the energy level jump of electrons inside the reactants, which leads to the change of charge distribution and chemical bonding properties in molecules. Compared with the traditional thermochemical reaction, photochemistry can mostly occur at room temperature or low temperature, which is characterized by energy saving and a green economy. In addition, another major feature of photochemical reactions is that the reaction is mild without the need to protect the groups, which greatly reduces the difficulty of compound synthesis. Therefore, in some conventional synthesis inserting a step photochemical reaction can greatly shorten the synthetic route, for organic synthesis provides an efficient and safe synthetic method.

Fig.1 Photocatalytic chemical reactions of chiral molecules.Fig.1 Photocatalytic synthesis of chiral compounds. (Hashemian, et al., 2024)

Our Photochemical Reaction Technology Platform

CD BioSciences-GreenChemistry's photochemical reaction technology platform provides process route development and optimization of photochemical reaction projects with photocatalytic reaction as the core, enabling process development from milligram to gram scale.

Photo-oxidation Design and Optimization

Based on the characteristics of the oxidation reaction, we select the most suitable type of light source and wavelength to catalyze the oxidation reaction under specific conditions (e.g., light intensity, reaction temperature, and time). To ensure the efficient operation of the photo-oxidation process, we also provide services such as catalyst selection, substrate preparation, and optimization of the reaction medium.

Schematic diagram of the precipitation method.

Photo-oxidation Reduction Design and Optimization

We design efficient photocatalytic redox reaction systems by combining reaction properties and objectives. We employ novel photosensitizers or photocatalytic systems to improve the selectivity and efficiency of the redox reaction and optimize the key parameters by adjusting the light intensity, temperature, and reaction time experimentally to develop an efficient and sustainable photocatalytic redox reaction process.

Schematic diagram of the precipitation method.

Photocatalytic Fluorination Design and Optimization

We provide the appropriate type of light source to determine the maximized catalytic efficiency. The optimal fluorination reaction is designed by adjusting the solvent type, reaction temperature, fluorination reagent, and substrate concentration to achieve the best reaction results. Next, the process of photocatalytic fluorination reaction is validated in a larger-scale reaction system to ensure its applicability in large-scale production.

Schematic diagram of the precipitation method.

Photocatalytic Nanoparticle Manufacturing Service

Based on the properties of the target nanoparticles, we select suitable materials and chemical precursors for composition and structure design to meet the photocatalytic reaction requirements. By adjusting the type of light source, reaction temperature, and time, we achieve the optimal synthesis of nanoparticles. In addition, we provide optimization of precursor solution ratios to ensure consistent nanoparticle size and morphology.

Details of Photochemical Reaction Technology Platform

  • Reactors: We have small photoreactors for small-scale laboratory reactions, as well as large factory-based photoreactors with capacities of more than 10 kg per day.
  • Temperature Control Range: -30 to 180°C
  • Light Source: Mercury or Xenon
  • Light Power: 100 to 1000W
  • Photocatalysts: A collection of common metal and organic catalysts, continually expanded based on the literature.

CD BioSciences-GreenChemistry's photocatalytic reaction technology platform has great innovation potential and effectively drives the chemical industry towards sustainability and environmental friendliness. Our photocatalytic reaction technology platform has several sets of light source equipment, which can meet the development of many new types of photochemical reactions. Please feel free to contact us if you are interested in our technology platform.

Reference

  1. Hashemian S.P., Zanjani S.M.A., et al. Photochemical and photocatalytic deracemization reactions[J]. SynOpen. 2024, 08(04): 232-246.

Our products and services are for research use only and cannot be used for any clinical purposes.