Polycaprolactone (IV 0.3-11)
| Catalog Number: | PCL-031 |
| Description: | Polycaprolactone (PCL) is a high molecular weight (>10,000) polymer obtained by ring-opening polymerization of caprolactone monomers and is supplied as granules or powder on request. |
Basic Information
| Formula | (C6H10O2)n |
| Applications | Polycaprolactone has good biocompatibility, degradability, and plasticity, and is now widely used in the medical field. First, polycaprolactone has the effect of promoting collagen regeneration. In the field of medical aesthetics, PCL is widely used in skin regeneration and repair. It can promote the regeneration and repair process of damaged skin by providing structural support and stimulating the formation of newborn substances. Research results show that PCL can improve the elasticity and smoothness of the skin, reduce the formation of wrinkles and scars, and restore the skin to a younger and healthier state. Secondly, in the medical field, polycaprolactone is used in the preparation of various medical devices and implants, such as surgical sutures, orthopedic splints, radiotherapy plates, resin bandages, dental impressions, artificial joints and cartilage repair materials. Due to its low toxicity and good biocompatibility, PCL can be compatible with human tissues and does not cause significant inflammatory reactions or rejection, so it is widely used as in vivo materials. In addition, in the field of tissue engineering, polycaprolactone is also widely used in the preparation of three-dimensional scaffolds, vascular substitutes and tissue-engineered organs. Drugs, growth factors and cells can be loaded into PCL scaffolds through nanotechnology to promote tissue repair, regeneration and regeneration. In addition, polycaprolactone can provide proper physical and structural support, promote cell adhesion and growth, and provide a good matrix for successful tissue engineering. In addition, the degradation rate of polycaprolactones can be modulated by changing the molecular weight and structure, thereby adapting them to different applications. For example, the degradation rate of PCL can be controlled by adjusting its molecular weight, thereby achieving long-term stability and durability of medical implants. In addition, the properties of polycaprolactone can be further improved by compounding with other materials and surface modification, such as enhancing its mechanical properties and bioactivity, to achieve better clinical results. |
| Appearance | White particles or powder |
| Melting Point (°C) | 60-70 |
| Monomer Residue (%) | ≤1 |
| Solvent Residue(ppm) | ≤0.5 |
| Total Heavy Metals (ppm) | ≤10 |
| Catalyst Residue (ppm) | ≤100 |
| Scorch Residue (%) | ≤0.5 |
| IUPAC Name | oxepan-2-one |
| SMILES | C1CCC(=O)OCC1 |
| InChi Key | PAPBSGBWRJIAAV-UHFFFAOYSA-N |
| Intrinsic Viscosity (dL/g) | 0.3-11 |
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