Polycaprolactone (MN 80000-100000)
| Catalog Number: | PCL-015 |
| Description: | Polycaprolactone (PCL) is a semi-crystalline hydrophobic biodegradable polyester that has a wide range of applications in the pharmaceutical field due to its low cost, toughness, and biocompatibility.PCL has some unique properties such as. It degrades slower than other biodegradable polyesters under physiological conditions, a property that can be used for controlled release of drugs from target tissues over a period of time. Due to its hydrophobicity, it has poor surface wettability and poor interaction with biofluids, leading to poor cell adhesion and proliferation, and hence is used in blends with other synthetic/natural polymers. |
Basic Information
| Formula | (C6H10O2)n |
| Synonyms | Hexanoic acid, 6-hydroxy-, lactone | 1219802-08-0 | e-Caprolactone--d6 | UNII-56RE988L1R | Hexanoic acid, 6-hydroxy-, .epsilon.-lactone | MFCD00084404 | Oxepan-2-one; Epsilon-Caprolactone | 1,6-Hexanolide | CHEBI:17915 | 2-Oxepanone | 6-Hydroxycaproic aci |
| Applications | Antibiotic-loaded PCL can be used to treat respiratory infections such as tuberculosis. Research has been done on the phenotypic response of human bone marrow mesenchymal stromal cells (hBMSCs) to different ratios of chitosan/polycaprolactone (PCL) blends. PCL/biomedical ceramic materials have been researched for possible bone tissue regeneration. PCL/graded insulin/beta-5 glycerophosphate concentrations on osteochondral tissue formation through adipose-derived stromal cell differentiation. Polycaprolactones are used as extrusion aids, die lubricants, mold release agents, pigment and filler dispersion aids, and polyester chain segments in polyurethanes and block polyesters. |
| Flash Point (°C) | >110°C |
| Melting Point (°C) | 60 |
| Number-Average Molecular Weight | 80000-100000 |
| Size | 5 g; 25 g; 100 g; 500 g; 2.5 kg |
| Features | Biodegradable polymers. Non-toxic, biodegradable in soil, excellent blendability, mechanically compatible with many polymers and good adhesion to many substrates. |
| Density (g/cm³) | 1.146 |
| IUPAC Name | oxepan-2-one |
| SMILES | C1CCC(=O)OCC1 |
| InChi Key | PAPBSGBWRJIAAV-UHFFFAOYSA-N |
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