• An NF-κB inhibitor with an IC₅₀ of 85 nM. It inhibits LPS-induced expression of TNF-α, IL-6, and MCP-1, exhibiting anti-inflammatory activity. It also shows antitumor efficacy (IC₅₀ for HCT-116 is 2 nM).
Bengamide B • An NF-κB inhibitor with an IC₅₀ of 85 nM. It inhibits LPS-induced expression of TNF-α, IL-6, and MCP-1, exhibiting anti-inflammatory activity. It also shows antitumor efficacy (IC₅₀ for HCT-116 is 2 nM).
| CAS No. | 104947-69-5 |
| Molecular Weight | 598.81 |
| Formula | C32H58N2O8 |
| SMILES | CC(C)/C=C/[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC)C(N[C@H]1CC[C@H](OC(CCCCCCCCCCCCC)=O)CN(C)C1=O)=O |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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