Chaetoglobosin A • Chaetoglobosin A, an active compound from Penicillium aquamarinium, belongs to the cytochalasan family and preferentially triggers apoptosis. It targets filamentous actin in chronic lymphocytic leukemia (CLL) cells, leading to cell cycle arrest and suppression of cell migration and membrane ruffling. It holds promise in actin-targeted cancer therapy.
| CAS No. | 50335-03-0 |
| Purity | 98.40% |
| Molecular Weight | 528.64 |
| Formula | C32H36N2O5 |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=C(/C=C/C1=O)[C@H](O)/C(C)=C/[C@@H](C)C/C=C/[C@]2([H])[C@]31C(N[C@@H](CC4=CNC5=C4C=CC=C5)[C@]3([H])[C@H](C)[C@]6(C)[C@@]2([H])O6)=O |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage |
Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 6 months; -20°C, 1 month |
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