Cytarabine • Cytarabine is a nucleoside analog that disrupts DNA synthesis by causing S-phase cell cycle arrest and inhibiting DNA polymerase. It has an IC₅₀ of 16 nM for DNA synthesis inhibition. Besides its anticancer properties, cytarabine also exhibits antiviral activity, particularly against herpes simplex virus (HSV) and orthopoxviruses.
| CAS No. | 147-94-4 |
| Purity | 99.98% |
| Synonyms | Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C |
| Molecular Weight | 243.22 |
| Formula | C9H13N3O5 |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=C1N=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)N |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage |
Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 2 years; -20°C, 1 year |
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