Dolastatin 10 • A powerful antimitotic peptide isolated from marine organisms. Dolastatin 10 inhibits tubulin polymerization, effectively arresting cell division. It is extensively studied in cancer research, especially for its potential in antibody-drug conjugate (ADC) development.
| CAS No. | 110417-88-4 |
| Purity | 98.11% |
| Synonyms | DLS 10; NSC 376128 |
| Molecular Weight | 785.09 |
| Formula | C42H68N6O6S |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | O=C([C@H](C)[C@H]([C@]1([H])CCCN1C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C([C@@H](NC([C@@H](N(C)C)C(C)C)=O)C(C)C)=O)C)=O)OC)N[C@@H](CC2=CC=CC=C2)C3=NC=CS3 |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage |
Sealed storage, away from moisture Powder: -80°C, 2 years; -20°C, 1 year The compound is unstable in solutions, freshly prepared is recommended. |
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