Hemiasterlin • Hemiasterlin is a cytotoxic marine tripeptide that acts as a potent antimitotic agent. It disrupts microtubule dynamics and shows strong anticancer activity. Hemiasterlin has been developed as a cytotoxic payload for use in antibody-drug conjugates (ADCs), with applications in targeted cancer therapy.
| CAS No. | 157207-90-4 |
| Purity | 99.77% |
| Synonyms | (-)-Hemiasterlin; Milnamide B |
| Molecular Weight | 526.71 |
| Formula | C30H46N4O4 |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | OC(/C(C)=C/[C@H](C(C)C)N(C)C([C@H](C(C)(C)C)NC([C@@H](NC)C(C)(C1=CN(C)C2=CC=CC=C12)C)=O)=O)=O |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage |
-20°C, protect from light In solvent: -80°C, 6 months; -20°C, 1 month (protect from light) |
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