Mycothiazole
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Catalog Number MDP-12874

Overview

• Mycothiazole is a mitochondrial electron transport chain (ETC) complex I inhibitor, showing cytotoxic effects on cancer cells such as Huh7 (IC₅₀ = 55.8 μM), U87, and MCF7. It induces apoptosis in Huh7 cells and utilizes the unfolded protein response (UPR) and heat shock response (HSR) pathways, involving transcription factors ATFS-1 and HSF1, to extend the lifespan of C. elegans.

Basic Information

CAS No. 114582-75-1
Molecular Weight 404.57
Formula C22H32N2O3S
SMILES COC(NCCC(/C=C\C[C@H](O)C(C)(C1=NC(C/C=C\CC=C)=CS1)C)=C)=O
Intended Use For research use only.

Package and Storage

Shipping Room temperature
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

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