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Poly(glycolide-co-lactide), 90:10, IV 1.7 dL/g 
Catalog Number BBP-0523
Product Name Poly(glycolide-co-lactide), 90:10, IV 1.7 dL/g
CAS Number 26780-50-7
Appearance Light yellow to tan solid
| Product Name | Poly(glycolide-co-lactide), 90:10, IV 1.7 dL/g |
|---|---|
| CAS Number | 26780-50-7 |
| Synonyms |
PLGA PLG Poly(lactic-co-glycolic acid) |
| Viscosity | ~1.7 dL/g [i.v.] |
| Appearance | Light yellow to tan solid |
| Shipping | Dry Ice |
| Biodegradation Time | ~ Weeks |
| Meta Description | CD BioSustainable offers high-quality Poly(glycolide-co-lactide) (PLGA) with tunable monomer ratios and molecular weights—FDA-approved, biodegradable, and ideal for drug delivery, tissue engineering, and biomedical research. Trust our expertise for your sustainable biomaterial needs. |
| Product Background |
Poly(glycolide-co-lactide), commonly abbreviated as PLGA, is a biodegradable and bioresorbable aliphatic polyester copolymer synthesized through the ring-opening copolymerization of two key monomers: glycolide (the cyclic dimer of glycolic acid) and lactide (the cyclic dimer of lactic acid). Its chemical structure is defined by repeating units of −(C₂H₂O₂)ₙ−(C₃H₄O₂)ₘ−, reflecting the random integration of glycolide and lactide segments. Due to the optical isomerism of lactide (which exists as L-lactide, D-lactide, and DL-lactide), PLGA can be further categorized into specific variants. For instance, the copolymer of glycolide and DL-lactide is often referred to as PGDLLA (poly(glycolide-co-DL-lactide)), while the combination of glycolide and L-lactide may be abbreviated as PGLA. It holds established CAS numbers, including 34346-01-5 and 26780-50-7, confirming its standardized identity in industrial and scientific contexts. In the field of biomaterials, PLGA has emerged as a cornerstone material, driven by the growing demand for biocompatible and degradable solutions in medical and research applications. Unlike non-degradable polymers that require surgical removal after use, PLGA’s design aligns with the body’s natural processes—its degradation products (lactic acid and glycolic acid) are metabolized and eliminated without toxic residue. This characteristic, coupled with its versatility, has made it a focus of both academic research and industrial innovation, with its development closely tied to advancements in drug delivery, tissue engineering, and regenerative medicine. |
| Product Advantages |
Exceptional Biocompatibility: It elicits minimal immune response or tissue irritation in the human body, making it safe for in vivo applications such as implantable devices and drug carriers. Predictable Biodegradation: Degradation occurs via ester bond hydrolysis, with rates precisely tunable by adjusting monomer ratio, molecular weight, and morphology—avoiding sudden material breakdown or toxic byproduct accumulation. Enhanced Drug Delivery Efficacy: Its porous structure and controllable degradation enable sustained, targeted drug release, prolonging therapeutic effects while reducing dosing frequency and systemic side effects. Eco-Friendly Profile: As a biodegradable polymer, it minimizes environmental impact post-use, aligning with sustainable research and manufacturing practices. |
| Product Applications |
Drug Delivery Systems: Widely used to fabricate microspheres, nanoparticles, and implants for controlled drug release. For example, PLGA nanoparticles can encapsulate chemotherapy drugs for targeted tumor delivery, or encapsulate vaccine antigens to enhance immunogenicity. It is also a key component in sustained-release formulations for chronic diseases, reducing patient adherence burdens. Tissue Engineering Scaffolds: Serves as a 3D framework for cell adhesion, proliferation, and differentiation in regenerative medicine. In bone tissue repair, porous PLGA scaffolds guide new bone growth and degrade gradually as healing progresses, eliminating the need for secondary scaffold removal surgery. It is also explored for periodontal tissue regeneration, such as guided tissue regeneration (GTR) membranes. Biomedical Devices: Used in the production of temporary medical devices, including absorbable sutures and wound dressings. Its combination of mechanical strength and biodegradability ensures devices function during healing and then disappear naturally. Cosmeceuticals: Incorporated into skincare formulations (e.g., anti-aging serums) as nanoparticle carriers for active ingredients, improving skin penetration and prolonged efficacy. |
| Related Products | Customers interested in Poly(glycolide-co-lactide) often explore other biodegradable aliphatic polyesters and their copolymers within the biomedical research space. Key related products include poly(lactic acid) (PLA) in its variants (L-PLA, D-PLA, DL-PLA), which offers tunable crystallinity for applications like sutures and cell culture scaffolds; poly(ε-caprolactone) (PCL), valued for its high drug permeability and shape-memory properties in long-term drug delivery; and PEG-conjugated copolymers such as MPEG-PLGA, PLGA-PEG-PLGA, and MPEG-PLA, which enhance hydrophilicity and temperature/pH sensitivity for advanced drug carriers. Additionally, poly(trimethylene carbonate) (PTMC) is a relevant option for elastic, biocompatible implants. If you are interested in related products, you can directly contact us or use our product customization service. |
Gloves & fume hood
Harmless - use normal precautions; Hygroscopic
Protect from moisture. Store at -20℃.
Customers interested in Poly(glycolide-co-lactide) often explore other biodegradable aliphatic polyesters and their copolymers within the biomedical research space. Key related products include poly(lactic acid) (PLA) in its variants (L-PLA, D-PLA, DL-PLA), which offers tunable crystallinity for applications like sutures and cell culture scaffolds; poly(ε-caprolactone) (PCL), valued for its high drug permeability and shape-memory properties in long-term drug delivery; and PEG-conjugated copolymers such as MPEG-PLGA, PLGA-PEG-PLGA, and MPEG-PLA, which enhance hydrophilicity and temperature/pH sensitivity for advanced drug carriers. Additionally, poly(trimethylene carbonate) (PTMC) is a relevant option for elastic, biocompatible implants. If you are interested in related products, you can directly contact us or use our product customization service.
CD BioSustainable is a well-known professional company in the industry. We provide a wide range of bio-environmental products, including bio-based materials, biomass fuels, green building materials, bio-environmental enzymes, bio-environmental microorganisms, etc. Please feel free to explore.
Our products and services are for research use only and cannot be used for any clinical purposes.
