Verrucarin J • Verrucarin J (Muconomycin B) is a secondary metabolite derived from the Myrothecium fungal genus. It promotes apoptosis in cancer cell lines such as A549, HCT 116, and SW-620 through ROS generation. Additionally, it exhibits antifungal activity against Candida albicans and Mucor miehei, and potently inhibits the arenavirus Junin (JUNV) with an IC₅₀ of 1.2 ng/mL. It is a compound of significant interest in both oncology and virology.
| CAS No. | 4643-58-7 |
| Purity | ≥99.0% |
| Synonyms | Muconomycin B |
| Molecular Weight | 484.54 |
| Formula | C27H32O8 |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | CC1=C[C@@H]2[C@]3(COC(/C=C(C)/CCOC(/C=C/C=C\C(OC4[C@]3(C)[C@@]5([C@H](O2)C4)CO5)=O)=O)=O)CC1 |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage |
Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 6 months; -20°C, 1 month |
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