Cladophorol A • A cGAS inhibitor that binds to the conserved adenosine nucleobase binding site of cGAS, blocking its activity. It inhibits the overactivation of the cGAS-STING pathway with an IC₅₀ of 370 nM, making it a potential research candidate for inflammatory diseases related to cGAS-STING pathway overactivation.
| CAS No. | 146776-30-9 |
| Molecular Weight | 260.20 |
| Formula | C13H8O6 |
| SMILES | O=C1OC2=CC(O)=C(C=C2C3=C1C=C(O)C(O)=C3)O |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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