Staurosporine • Staurosporine is a highly potent, ATP-competitive, and broad-spectrum protein kinase inhibitor. It exhibits inhibitory activity with IC₅₀ values of 6 nM for PKC, 15 nM for PKA, 2 nM for c-Fgr, and 3 nM for phosphorylase kinase. Additionally, it inhibits TAOK2 with an IC₅₀ of 3 μM. Staurosporine is well-known for its role in inducing apoptosis.
| CAS No. | 62996-74-1 |
| Purity | 99.98% |
| Synonyms | Antibiotic AM-2282; STS; AM-2282 |
| Molecular Weight | 466.53 |
| Formula | C28H26N4O3 |
| Appearance | Solid |
| Color | White to yellow |
| SMILES | O=C(NC1)C2=C1C3=C(C4=C2C5=C(C=CC=C5)N4[C@H]6C[C@@H](NC)[C@@H](OC)[C@]7(C)O6)N7C8=CC=CC=C83 |
| Intended Use | For research use only. |
| Shipping | Room temperature |
| Storage |
Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 1 year; -20°C, 6 months |
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